Liss made a good start with the ball with opening bowlers Blanks and Charles putting the pressure on.
Charles made the breakthrough in the second over when he dismissed opening batsman Vincent for one.
A run out was quickly followed by two wickets for Blanks which left the visitors struggling on 11-4.
Hopkins joined Webber at the crease and the pair set about digging in.
Picking off the bad balls, Webber and Hopkins started to build a partnership and kept the score ticking.
Webber and Hopkins both reached their half-centuries, and the pair had put on a 117-run partnership before the spin of Dillon-Thiselton picked up two wickets in three overs to leave the visitors on 142-6.
Webber reached 75 before bowling debutant Clarke had him caught behind and the visitors finished on 189-8 at the end of their 45 overs.
Liss openers Kemp and Hannam made a positive start, taking 18 from the first four overs, before Kemp played on for 12.
Moore joined Hannam at the crease and the hosts reached 34-1 before losing five wickets for just 14 runs to slip to 48-6.
Clarke (20) and Allcock (23) then added 39 before Clarke played on and Allcock was caught behind.
Liss were struggling at 101-8 and the home side were only able to add a further 11 runs before being dismissed for 112 to lose by 77 runs.